Gene description for Tgfbr2
Gene name	transforming growth factor, beta receptor II
Gene symbol	Tgfbr2
Other names/aliases	1110020H15Rik DNIIR RIIDN TBR-II TbetaR-II TbetaRII
Species	Mus musculus
Experiment description of studies that identified Tgfbr2 in Breast cancer cells
1 Experiment ID 1054 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 29115712    Organism Mus musculus Experiment description Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Authors Gangoda L, Liem M, Ang CS, Keerthikumar S, Adda CG, Parker BS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Breast cancer cells Sample name 4T1.2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
2 Experiment ID 1967 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35915084    Organism Mus musculus Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry Immuno-EM Flow cytometry ELISA EV-TRACK -
3 Experiment ID 1967 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35915084    Organism Mus musculus Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry Immuno-EM Flow cytometry ELISA EV-TRACK -
4 Experiment ID 1996 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Mass spectrometry PubMed ID 34112803    Organism Mus musculus Experiment description Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Authors Lima LG, Ham S, Shin H, Chai EPZ, Lek ESH, Lobb RJ, Müller AF, Mathivanan S, Yeo B, Choi Y, Parker BS, Möller A. Journal name Nat Commun Publication year 2021 Sample Breast cancer cells Sample name EO771 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Centrifugal ultrafiltration Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry EV-TRACK -
5 Experiment ID 1997 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Mass spectrometry PubMed ID 34112803    Organism Mus musculus Experiment description Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Authors Lima LG, Ham S, Shin H, Chai EPZ, Lek ESH, Lobb RJ, Müller AF, Mathivanan S, Yeo B, Choi Y, Parker BS, Möller A. Journal name Nat Commun Publication year 2021 Sample Breast cancer cells Sample name PyMT Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Centrifugal ultrafiltration Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry EV-TRACK -
6 Experiment ID 1967 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Immuno-EM PubMed ID 35915084    Organism Mus musculus Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry Immuno-EM Flow cytometry ELISA EV-TRACK -
7 Experiment ID 1967 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Flow cytometry PubMed ID 35915084    Organism Mus musculus Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry Immuno-EM Flow cytometry ELISA EV-TRACK -
8 Experiment ID 1967 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method ELISA PubMed ID 35915084    Organism Mus musculus Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry Immuno-EM Flow cytometry ELISA EV-TRACK -
9 Experiment ID 1973 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method ELISA PubMed ID 35915084    Organism Mus musculus Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study ELISA EV-TRACK -